Encephalitis Associated with Influenza B Virus Infection in 2 Children and a Review of the Literature
Identifieur interne : 001713 ( Main/Exploration ); précédent : 001712; suivant : 001714Encephalitis Associated with Influenza B Virus Infection in 2 Children and a Review of the Literature
Auteurs : Jason G. Newland [États-Unis] ; José R. Romero [États-Unis] ; Meera Varman [États-Unis] ; Casey Drake [États-Unis] ; Amy Holst [États-Unis] ; Tom Safranek [États-Unis] ; Kanta Subbarao [Géorgie (pays)]Source :
- Clinical Infectious Diseases [ 1058-4838 ] ; 2003.
Abstract
Two children with influenza B-associated encephalitis (IBAE) presented to our hospital during the winter of 2000–2001, both of whom had cases notable for mutism in association with encephalitis. A review of the literature identified 13 additional reports consistent with IBAE that contained sufficient data for analysis. Eleven of 15 reported cases occurred in children aged ⩽18 years; of these, more than one-half occurred in children <11 years of age. Neurologic symptoms appeared within the first 4 days of illness in 13 cases. Speech abnormalities were observed in 4 patients and consisted of mutism in 3. Although the majority of patients recovered fully, 3 were left with neurologic sequelae, and 1 died. These cases reveal the spectrum of IBAE and its potential for long-term sequelae. Clinicians caring for children should remain vigilant for this rare complication of influenza B virus infection.
Url:
DOI: 10.1086/368184
Affiliations:
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<front><div type="abstract">Two children with influenza B-associated encephalitis (IBAE) presented to our hospital during the winter of 2000–2001, both of whom had cases notable for mutism in association with encephalitis. A review of the literature identified 13 additional reports consistent with IBAE that contained sufficient data for analysis. Eleven of 15 reported cases occurred in children aged ⩽18 years; of these, more than one-half occurred in children <11 years of age. Neurologic symptoms appeared within the first 4 days of illness in 13 cases. Speech abnormalities were observed in 4 patients and consisted of mutism in 3. Although the majority of patients recovered fully, 3 were left with neurologic sequelae, and 1 died. These cases reveal the spectrum of IBAE and its potential for long-term sequelae. Clinicians caring for children should remain vigilant for this rare complication of influenza B virus infection.</div>
</front>
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<region><li>Nebraska</li>
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<name sortKey="Newland, Jason G" sort="Newland, Jason G" uniqKey="Newland J" first="Jason G." last="Newland">Jason G. Newland</name>
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<name sortKey="Romero, Jose R" sort="Romero, Jose R" uniqKey="Romero J" first="José R." last="Romero">José R. Romero</name>
<name sortKey="Romero, Jose R" sort="Romero, Jose R" uniqKey="Romero J" first="José R." last="Romero">José R. Romero</name>
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